Rami Hannoush, Ph. … | 77 comments on LinkedInComing out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. We are a creative and multidisciplinary team of scientists, innovators and leaders dedicated to changing the way we approach drug development by establishing a powerful small. 4d Edited. , USA) "Challenges and Emerging Approaches in Peptide Drug Discovery" 9:25 am - 9:40 am: Discussion. I am thankful for the LPs, founders, CEOs, team members who have remained steadfast partners over the years in using advanced technology to build a better… | 13 comments on LinkedInRami Hannoush, co-founder and interim CEO of EpiBiologics, discusses the company’s platform technology, how its protein degradation approach expands the potential targets for its therapies; and. Read top stories published by MubadalaVentures. ’s Post Rami Hannoush, Ph. Inventors: Eric Bourhis, Rick Carano, Andrea Cochran, Mike Costa, Venita DeAlmeida, James Ernst, Yan Gong, Rami Hannoush, Paul Polakis, Bonnee Rubinfeld, Mark. 120. Rami Hannoush, Ph. Ribonucleic acids (RNA) are polymers of ribonucleotides linked together by 3',5'-phosphodiester linkages and play a prominent role in protein biosynthesis. ’s Post Rami Hannoush, Ph. Baig et al. Marianne Mertens, [email protected]. Healthcare VC at Versant | Life sciences company creation | Former R&D leader, Genentech | Former CEO, EpiBiologics 1y. His current role includes leading interdisciplinary teams in lead discovery and research biology, with the overarching goal of developing therapeutics for the. H. D. The author has an hindex of 28, co-authored 68 publications receiving 2989 citations. 05. A fascinating approach to degrade membrane proteins/receptors. D. Expand search. . Rami Hannoush, Ph. com . A fascinating approach to degrade membrane proteins/receptors. Rami Hannoush, Ph. “Dysregulation of normal cellular differentiation processes can alter normal cell biology leading to tumor formation and progression,” said Dr. Rami Hannoush has been working as a Chief Executive Officer & Co-Founder & Member Board of Directors at EpiBiologics for 8 months. ’s Post Rami Hannoush, Ph. One of the toughest things about handing off your bookkeeping is figuring out what to do with all your extra time. Synthetic protein lipidation. Rami Hannoush’s Post Rami Hannoush General Partner, Mubadala Capital | Healthcare VC | Life sciences company creation 4d Report this post. D. D. The design of clickable fatty acid probes is based on the introduction of a small chemical tag (alkyne or azide) at the ω or methyl end of the fatty acid (Figure 2). Professor Nagy Habib is Head of Surgery at the Hammersmith Campus of Imperial College London and also a serial founder and entrepreneur of life sciences ventures. Hannoush is a general partner at Mubadala Capital, the financial investment arm of the Sovereign Wealth Fund Mubadala. D. Citizen and Immigration Services 2019 Outstanding Americans by. rami@gene. cbpa. Schedule view. D. Healthcare VC | Life sciences company creation 1y 2021 Innovative Medicines Fifty new drugs were FDA approved that help improve the health of patients with unmet medical needs. Rami Hannoush: Chemical tools to perturb and image Wnt signaling: Danica Galonic Fujimori: 3/15/12: Harmit Malik, Fred Hutchinson Cancer Center: Genetic conflicts: the usual suspects and beyond: John Gross: 4/5/12: Ian Wilson, Scripps: Broad neutralization of HIV and influenza viruses: Bob Stroud:It started with a cup of coffee and a slow burning desire to go early and long in the biotech creation business. Rami Hannoush is the co-founder, interim CEO and president of EpiBiologics. D. Coming out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. ’s Post Rami Hannoush, Ph. Marianne Mertens, Ph. cbpa. Verified email at post. Rami Hannoush, Department of Early Discovery Biochemistry, Genentech. Rami Hannoush, EpiBiologics is building a protein degradation platform that targets membrane and extracellular proteins. interim CEO and co-founder of EpiBiologics and venture partner at Versant Ventures. THE AURON TEAM A CULTURE OF INNOVATION. D General Information. Rami Hannoush has 2 current jobs as General Partner at Mubadala Capital Ventures and Co-Founder at EpiBiologics. Lives in San Mateo, CA. Yen, founder and CEO. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 6d EditedRami Hannoush, Ph. Currently teaching. Lee-Karlon left another Bay Area biotech company, Altos Labs, in June, according to her LinkedIn. Marianne Mertens, Ph. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 2mo Report this post Report Report. EpiBiologics's CEO is Rami Hannoush What does EpiBiologics do? Founded in 2022, EpiBiologics is a biotechnology company with a focus on antibody-based protein degradation. D. Rami Hannoush, Ph. EpiBiologics develops antibody-based targeted therapies against. “Dysregulation of normal cellular differentiation processes can alter normal cell biology leading to tumor formation and progression,” said Dr. D. Coming out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. Hannoush has filed for patents to protect the following inventions. Rami Hannoush, Genentech, South San Francisco, USA 5:25 pm General Discussion, Day 2 Wrap-Up 6:00 pm Reception, dinner . Healthcare VC | Life sciences company creation 6dRami Hannoush, Ph. Search for more papers by this author Speakers – APS 2022. Rami Hannoush, co-founder and interim CEO of EpiBiologics, discusses the company’s platform technology, how its protein degradation approach expands the potential targets for its therapies; and. Question: Add details. D. … | 77 comments on LinkedInRami Hannoush, Ph. D. Contents: Chemical Synthesis S2 . Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 2mo Report this post Report Report. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 1y EditedRami Hannoush, Ph. interim CEO and co-founder of EpiBiologics and venture partner at Versant Ventures. Proud to partner with a great team to systematically explore the untapped therapeutic potential of…“We would like to thank Rami Hannoush for his leadership as co-founder and interim CEO and look forward to an exciting next stage of growth for EpiBiologics under Ann’s leadership. The Frizzled (FZD) 7 receptor (FZD7) is enriched in LGR5 + intestinal stem cells and plays a critical role in their self-renewal. D. It’s been a terrific two days at #jpm2023, meeting new talent and connecting with friends in pharma and the VC world. Scheme 2 S3 . Born on September 20th, 1976 (47 years old)Rami Hannoush, Ph. Scroll Top. Rami N. S. D. , 1 DNA Way, South San Francisco, CA 94080, USA. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 3mo. Recent News and Activity. Back. … | 79 comments on LinkedInRami Hannoush, Ph. Healthcare VC | Life sciences company creation 6dRami Hannoush, Ph. D. Expand search. Hannoush and Phil S. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 1mo Report this post Report Report. Stablix is pioneering an entirely new field of targeted deubiquitination therapeutics (TDT) to bring transformative medicines to patients with unmet medical need. Patrick Sexton, Monash University. Search for a company, investor, advisor, limited partner, fund or professional to preview their profile. 2015. Rami Hannoush has 2 current jobs as General Partner at Mubadala Capital Ventures and Co-Founder at EpiBiologics. Hannoush include Harvard University & Scripps Research Institute. D. Rami Hannoush, Ph. 1007/978-1-61779-349-3_7 Abstract Methods to detect and characterize cellular protein myristoylation and palmitoylation are invaluable in cell biology, immunology, and virologyXinxin Gao, Natalia Arenas-Ramirez, Suzie Scales and Rami Hannoush performed experiments. , Partner at Apollo Health Ventures, will join the Company as Board observers. Rami Hannoush, Ph. Rami N. He also recently joined Versant Ventures (as a venture partner) where he works on biotech company creation and life science investments. According to LinkedIn Rami Hannoush started working on 2006, then the employee has changed 9 companies and 12 jobs. CSB 243: Biotechnology and Development of Therapeutics (Autumn)9 Department of Early Discovery Biochemistry, Genentech, South San Francisco, CA, USA. Coming out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. D. Vlieghe et al. Back. Supplementary Text and Figures. Yet, how different Wnts achieve various levels of signaling activation through distinct domains on LRP6 remains elusive. D. Thrilled to share this work from my former group at Genentech, reporting on a new class of peptide agonists that modulate. "To our knowledge, no one has identified ligands that bind to the zymogen," said senior author Rami Hannoush, Genentech, South San Francisco, California. … | 76 comments on LinkedInComing out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. D. Supplementary Figures 1–7, Supplementary Tables 1–3 and Supplementary Methods. ’s Post Rami Hannoush, Ph. Rami Hannoush, co-founder and interim CEO of EpiBiologics, discusses the company’s platform technology, how its protein degradation approach expands the potential targets for its therapies; and. Rami N Hannoush, Ph. Fatty acylation of proteins is a versatile co-translational or post-translational modification that plays a key role in human. D. 05. Biomarker interview with Rami Hannoush, Ph. ’s Post Rami Hannoush, Ph. Aaron H Nile & Rami N Hannoush* Wnt proteins are critical regulators of signaling networks during embryonic development and in adult tissue homeostasis. J Pharm Sci 2022 07 10;111(7):1896-1910. D. Currently teaching. . Rami Hannoush, Ph. Our mission is to partner with visionary founders building enduring technology companies, and support them with Mubadala’s global scale, resources. degree at McGill University. Rami Hannoush, Ph. D. Supplementary Figure 1 S5 . D. degree at. … | 76 comments on LinkedInComing out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. Rami N Hannoush is part of Stanford Profiles, official site for faculty, postdocs, students and staff information (Expertise, Bio, Research, Publications, and more). Rami Hannoush (Genentech, Inc. Rami Hannoush, Ph. . Specific lab interests include Wnt signaling, protein. interim CEO and co-founder of EpiBiologics and venture partner at Versant Ventures. Inventors: Eric Bourhis, Tim Cao, Rick Carano, Andrea Cochran, Mike Costa, Venita DeAlmeida, James Ernst, Yan Gong, Rami Hannoush, Paul Polakis, Bonnee Rubinfeld, Mark Solloway, Yan Wu METHODS AND COMPOSITIONS FOR MODULATING THE Wnt PATHWAY Protein palmitoylation plays diverse roles in regulating the trafficking, stability, and activity of cellular proteins. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 2mo Report this post Report Report. EpiBiologics’s CEO is Rami Hannoush Who are EpiBiologics key employees? Some of EpiBiologics key employees are Craig Lichtenstein Where is EpiBiologics located? EpiBiologics’s headquarters are located at 1900 Alameda De Las Pulgas Ste 250, San Mateo, California, 94403, United States How do I contact. Rami Hannoush, Ph. Rami Hannoush, EpiBiologics is building a protein degradation platform that targets membrane and extracellular proteins. Competing interests. degree at McGill University. Search for more papers by this author. Rami Hannoush Manage my profile. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 10mo EditedGreat chat with Ron Leuty from San Francisco Business Times to share our story on building EpiBiologics #companybuilding #degradation | 37 Kommentare auf LinkedInIn an interview with BioPharma Dive: Biotech and Pharma news, our co-founders Jim Wells and Rami Hannoush discussed the company's origin and EpiBiologics' differentiated protein degradation approach. View the profiles of professionals named "Rami D" on LinkedIn. Human OS cell lines (MNNG/HOS, MG-63, and U2-OS) were treated with increasing concentrations of dynasore or cisplatin, and then the cell. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 2mo Report this post Report Report. Rami Hannoush, education was also an escape. D. ’s Post Rami Hannoush, Ph. Copy Link. Rami Hannoush. From a previous marriage, he has a three-year-old son. com. … | 76 comments on LinkedInComing out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. D. D. He also recently joined Versant Ventures (as a venture partner) where he. hannoush. Its proprietary EpiTAC platform is a. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 2mo Report this post Report Report. com. The Frizzled (FZD) 7 receptor (FZD7) is enriched in LGR5 + intestinal stem cells and plays a. Connect Lana Janes, Ph. San Mateo, California, United States 4K followers 500+ connections See your mutual connections Join to follow Versant Ventures Harvard University. 2017. Back. ’s Post Rami Hannoush, Ph. Rami Hannoush, Ph. D. Coming out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. Rami Hannoush, Dr. … | 80 comments on LinkedInRami Hannoush’s Post Rami Hannoush General Partner, Mubadala Capital | Life sciences company creation | Chief Scientific Officer 10mo Report this post. Alanna Schepartz, The University of California, Berkeley. Drug Discovery & Development Oncology Wnt and Stem Cells Peptide Therapeutics. D. Rami Hannoush, Ph. Rami Hannoush is a co-founder, President and interim CEO of EpiBiologics. CSB 243: Biotechnology and Development of Therapeutics (Autumn) Regeneration of the adult intestinal epithelium is mediated by a pool of cycling stem cells, which are located at the base of the crypt, that express leucine-rich-repeat-containing G-protein-coupled receptor 5 (LGR5). , for the launch of [email protected]. D. D. The Section of Hematology/Oncology, within the Department of Internal Medicine, Max Rady College of Medicine, in affiliation with CancerCare Manitoba (CCMB) as the Department. D. He focuses on early. … | 76 comments on LinkedInComing out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. Back. I had the pleasure to join Rob Faulkner and Soo. Background. Rami N Hannoush Adjunct Professor, Chemical and Systems Biology Operations Print Profile Email Profile Bio Bio Professional Contact. D. … | 79 comments on LinkedInRami Hannoush, Ph. Healthcare VC | Life sciences company creation 2yThe 2020 Chemistry and Biology of Peptides Gordon Research Conference will showcase the most recent, cutting edge research in advancing peptides as tools, materials, and therapeutics. BSMB Spring meeting 2022: "Interactions between Lipids/derivatives and the ECM: pre-clinical and clinical relevance" Registration for BSMB members is FREE, £10 and £30 respectively for student. 1038/s41589-018-0035-2 Abstract Regeneration of the adult intestinal epithelium is mediated by a pool of cycling stem cells, which are located at the base of the crypt, that express leucine-rich-repeat-containing. ’s Post Rami Hannoush, Ph. Hannoush joined the Early Discovery Biochemistry department at Genentech in 2006 after completing his postdoctoral fellowship at Harvard and his Ph. … | 76 comments on LinkedInComing out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. D. Rami Hannoush, co-founder and interim CEO of EpiBiologics, discusses the company’s platform technology, how its protein degradation approach expands the potential targets for its therapies; and. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 2mo Report this post Report Report. Headquarters Regions San Francisco Bay Area, Silicon Valley, West [email protected] N Hannoush, Ph. ’s Post Rami Hannoush, Ph. Rami Hannoush has been working as a General Partner | US Ventures for Mubadala for 456 days. There are 3 professionals named "Rami Hannoush", who use LinkedIn to exchange information, ideas, and opportunities. ’s Post Rami Hannoush, Ph. S. Rami Hannoush, Ph. D. D. We cover Rami's new role at. Coming out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. Healthcare VC | Life sciences company creation. Rami Hannoush is the Chief Executive Officer (interim), President and a co-founder of EpiBiologics. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 7mo Report this post What are some of the factors that contribute to aging? And could we identify the specific mechanisms by which these factors impair tissue regeneration?Rami Hannoush, Ph. PMID: 31152407 DOI: 10. … | 79 comments on LinkedInCongratulations to our own Rami Hannoush, Principal Scientist, Early Discovery Biochemistry, for being one of ten to receive the U. Baran . Rami Hannoush 5d · Edited Report this post Report Report. D. Shawn Zhang Karthik Nagapudi Mike Shen Joshua Lomeo Yuri Qin Aiden Zhu Purnendu Nayak Debby Chang Rami N Hannoush. It is tightly controlled by a set of enzymes which catalyze the covalent attachment of fatty. hannoush. D. D. Symposium Sponsors. Rami Nabil Hannoush, Rami Hannoush, Ramin Hannoush. Operating Status Active. D. Expand search. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 1mo Report this post Report Report. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO). Xinxin Gao, Xinxin Gao. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 2mo Report this post Report Report. , as Chief Data Officer,. EpiBiologics Co-Founder. 4 the Department of Early Discovery Biochemistry, Genentech, South San Francisco, California 94080, and hannoush. Name & Title Social Contact Info; Craig Lichtenstein. Healthcare VC | Life sciences company creation 1wRami Hannoush, 45. interim CEO and co-founder of EpiBiologics and venture partner at Versant Ventures. D. Jumi Shin, University of Toronto. Founded in 2022 and led by CEO Dr. D. . Healthcare VC | Life sciences company creation 1yRami Hawash is the owner of a car mechanical repair business in Romford, Essex. Schneider, National Cancer Institute – Center for Cancer Research. D. Scalable Total Synthesis and Biological Evaluation of Haouamine A and Its Atropisomer. Skip to main content Due to a planned power outage on Friday, 1/14, between 8am. Manage my profile. , as Chief Scientific Officer, Thomas Graeber, Ph. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 4mo Edited Report this post At last, after 43 years since the discovery of the Wnt gene, the structure of the ternary Wnt – Frizzled – LRP6 signaling complex is reported here, and it provides a blueprint that. Rami N. Back. At last, after 43 years since the discovery of the Wnt gene, the structure of the ternary Wnt – Frizzled – LRP6 signaling complex is reported here, and it…Many proteins have been found to be regulated through S-palmitoylation, a highly conserved process occurring in all eukaryotic organisms that involves the attachment of 16-carbon fatty acids onto cysteine residues via a reversible thioester linkage (Chamberlain and Shipston, 2015, Hannoush, 2015). Wrapping up a 15-year discovery stint at Genentech back in the summer of 2021, Rami. The small size of the chemical tag is meant to minimize interference with fatty acyltransferase substrate recognition and catalytic efficiency (Hannoush, 2015, Hannoush and Arenas-Ramirez, 2009). Healthcare VC | Life sciences company creation | Former R&D leader, GenentechComing out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. D. ’s Post Rami Hannoush, Ph. Rami Hannoush’s Post. “We would like to thank Rami Hannoush for his leadership as co-founder and interim CEO and look forward to an exciting next stage of growth for EpiBiologics under Ann’s leadership. Healthcare VC | Life sciences company creation 6dRami Hannoush, Ph. For info and…Biomarker sits down with Rami Hannoush, General Partner at Mubadala Capital Ventures. D. Coming out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. Rami Hannoush, Ph. We cover Rami's new role at Versant, the founding story of. We cover Rami's new role at Versant, the founding story of. D. Rami Hannoush, PhD. 388. D. D. PubMed Abstract: Regeneration of the adult intestinal epithelium is mediated by a pool of cycling stem cells, which are located at the base of the crypt, that express leucine-rich-repeat-containing G-protein-coupled receptor 5 (LGR5). ’s Post Rami Hannoush, Ph. Rami Hannoush, Ph. ’s Post Rami Hannoush, Ph. Profile Previews—Driven by the PitchBook Platform. We cover Rami's new role at Versant, the founding story of. D. PMID: 28377511 PMCID: PMC5402412 DOI: 10. D. This button displays the currently selected search type. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 1w EditedRami Hannoush; Found 5 results for your query: Rami Hannoush in the United States of America. Rami has 3 jobs listed on their profile. D. , 1 DNA Way, South San Francisco, CA 94080, USA. Healthcare VC | Life sciences company creation 6 TageThank you Ayman, Alaa, and Rami for your trust and support! Could not have asked for better partners. Back. , Partner at Apollo Healthcare Ventures, will join the Company as Board observers. On average, Rami Hannoush works for one company for 2 years 7 months. 19th Ave New York, NY 95822, USA. … | 76 comments on LinkedInComing out of stealth mode, I'm thrilled to announce the unveiling of EpiBiologics, a biotech company advancing a next-generation protein degradation platform. ’s Post Rami Hannoush, Ph. D. Biomarker interview with Rami Hannoush, Ph. The site facilitates research and collaboration in academic endeavors. Rami Hannoush, EpiBiologics is building a protein degradation platform that targets membrane and extracellular proteins. D. Rami Hannoush has been working as a General Partner | US Ventures for Mubadala for 456 days. Wrapping up a 15-year discovery stint at Genentech back in the summer of 2021, Rami. D. Hannoush is an academic researcher from Genentech. D. “Jim and I have known each other for the past 15 years through Genentech. When expanded it provides a list of search options that will switch the search inputs to match the. ’s Post Rami Hannoush, Ph. Apply now and find other jobs on WIZBIIRami Hannoush, Ph. D. ’s Post Rami Hannoush, Ph. Rami Hannoush is the co-founder, interim CEO and president of EpiBiologics. , Partner at Mubadala Capital, and Dr. D. Hannoush. degree at McGill University. Rami Hannoush ExploreCourses 2019-2020 2020-2021 2021-2022 2022-2023 2023-2024 Browse by subject. Healthcare VC | Life sciences company creation | Former R&D leader, Genentech 6mo Edited Report this post. D. Lee-Karlon served as Chief Operating Officer of Altos Labs. Back. EpiBiologics is part of the Business Services industry, and located in California, United States. When expanded it provides a list of search options that will switch the search inputs to match the. 025 Abstract Fatty acylation of proteins is a versatile co-translational or post-translational modification that plays a key role in human physiology and disease. The site facilitates. Cunningham5,* 1Department of Structural Biology 2Center for Advanced Light Microscopy 3Department of Protein Chemistry 4Department of Discovery Oncology 5Department of Early Discovery Biochemistry Genentech, Inc. Alanna Schepartz, The University of California, Berkeley. D. Joel P. The American Peptide Society, APS, a nonprofit scientific and educational organization founded in 1990, provides a forum for advancing and promoting knowledge of the chemistry and biology of peptides. has lived in San Mateo, CA Watertown, MA 1200 Massachusetts Ave, Cambridge, MA 02138 Foster City, CA. We are dedicated to bridging ideas from academia with the cutting edge in biotechnology and translation. Our group described u-alkyne fatty acids of various chain lengths (C10, C11, C13, C14, C16, and C18, with the alkyne group at the u position) (Figure 2) and showed the Wrapping up a 15-year discovery stint at Genentech back in the summer of 2021, Rami Hannoush was treated to a caffeine-fueled review of the latest work UCSF’s Jim Wells had been doing on protein degradation — one of the hottest fields in drug development. Rami Hannoush is a venture partner operating across San Diego and the San Francisco Bay Area. D. PMID: 30530496 PMCID: PMC6333880 Rami Hannoush, interim-CEO, said, “Since launching the company, the team at EpiBiologics has been able to further validate and industrialize the EpiTAC platform, creating a fit-for-purpose atlas of degraders. rami@gene. hannoush. Rami Hannoush, Ph. D. English. Lee-Karlon served as. However, the specificity of the interaction between mammalian WNT and FZD proteins and the subsequent signaling cascade downstream.